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IGF-I acts predominantly via the IGF-I receptor (IGF-IR), a transmembrane protein consisting of two extracellular -subunits, which contain the IGF-I binding site, and two transmembrane -subunits that have a cluster of three tyrosine residues, which undergo phosphorylation and activation upon IGF-I binding to mediate canonical signaling pathways necessary for cell survival and growth

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Additionally, Ipamorelin boasts an enhanced safety profile, making it preferable over other GH-releasing agents

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