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A more recent study found that following cytarabine chemotherapy, the enriched-senescent AML cells produced a senescence-associated secretory phenotype (SASP) by increasing NF-B transcription through the ataxia telangiectasia and Rad3-related (ATR) activities, and regained stemness properties sufficient to restore leukemia (129)
Genet Neurol Behav Diet Dement:739748
Brains were cut using a razor blade down the midline evenly to separate hemibrains and each hemibrain was transferred into a 1.5 mL microcentrifuge tube containing neurobasal complete media used in cortical Primary Cortical Neuron Culture Maintenance described above
