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Following Hg exposure, the red blood cell (RBC) to plasma Hg concentration ratio typically ranges between 1:1 and 2:1 (WHO, 1991)

These components act through a variety of mechanisms including decreasing inflammatory mediator production through effects on cell signalling and gene expression, reducing the production of damaging oxidants and promoting gut barrier function and anti-inflammatory responses (Figure 3)

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These three trials included a broader disease spectrum, with rare diseases represented as subgroups
Vanhoefer, U