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Designing gRNAs for CRISPR interference is complex and requires precise targeting of regulatory regions near the transcription start site

Concerns about the transfer of pathogenic microorganisms, alterations in gut microbiota composition, and unintended metabolic effects necessitate further investigation to ensure patient safety (Matzaras et al., 2022)

In: Bonagura J, editor

"Folic Acid Supplementation and the Risk of Cardiovascular Diseases: A Meta-Analysis of Randomized Controlled Trials" (PDF)

doi:10.1177/1129729819877323
