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The peptide activates extracellular signal-regulated kinase 1/2 (ERK1/2) phosphorylation in a dose-dependent manner, leading to nuclear translocation and activation of transcription factors including c-Fos, c-Jun, and early growth response-1 (Egr-1) that drive expression of genes involved in cell growth, migration, and angiogenesis

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It won't be instant, but over 3-6 months, you may see the laxity improve

[DOI] [PMC free article] [PubMed] [Google Scholar] 28.Pahwa R., Goyal A., Bansal P., Jialal I

As such, we may struggle to absorb the vitamin B12 from food