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The TPH1 gene is located on chromosome 11p15.1 and is composed of 11 exons that encode a protein (tryptophan 5-hydroxylase 1) of 444 amino acids
Montenegro L, Turnaturi R, Parenti C, Pasquinucci L (2018) Idebenone: novel strategies to improve its systemic and local efficacy
10.1016/j.redox.2024.103288 Redox Biol
The ketone body beta-hydroxybutyrate mitigates ILC2-driven airway inflammation by regulating mast cell function
The persistence of effects without continuous receptor occupation suggests DSIP may trigger gene expression changes rather than requiring constant pharmacological presence
