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This enables precision interventions: DGAT1 inhibitors for APOE 4 carriers with astrocytic lipid droplets [90, 98, 99, 270], or NAD + salvage for aged SIRT1-deficient penumbras with NAMPT variants [244, 245]
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Thus, inhibition of HDACs by BHB would directly contribute to chromatin remodeling and subsequent changes in the gene expression profile
Annals of the New York Academy of Sciences , 1033 (1), 30-41
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