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Unveiling the therapeutic potential of taxifolin in cancer: from molecular mechanisms to immune modulation and synergistic combinations

Combination of PI3K- and CDK4/6-inhibitors overcame the intrinsic and acquired resistance of breast cancers to PI3K-inhibitors, and resulted in regression of PIK3CA -mutant xenografts (88)

[DOI] [PubMed] [Google Scholar] 55.Hochgesang G.P., Rowlinson S.W., Marnett L.J
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Further, a secondary analysis of a trial in women at high risk for or with existing cardiovascular disease reported that high-dose supplemental B-vitamins (1 mg/day of vitamin B 12 , 50 mg/day of vitamin B6, and 2.5 mg/day of folic acid) for 7.3 years had no effect on risk of non-vertebral fractures (122)
