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This study aimed to examine the longitudinal trajectory of these symptoms, classify distinct symptom cluster profiles, uncover symptom interconnections, identify core symptoms, and explore associated factors

It includes conditions such as emphysema and chronic bronchitis, which are typically caused by long-term exposure to irritants such as cigarette smoke, air pollution, and chemical fumes

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The finding that master TFs regulate the N-response cascade suggests that maize and Arabidopsis share an N-response GRN

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