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184,185 The pathophysiology of DRPN involves ischemic injury due to microvasculitis leading to nerve fiber ischemia and immune-mediated mechanisms, as evidenced by inflammatory infiltrates in nerve biopsies

DSIP has been investigated across multiple contexts, including sleep disorders, pain modulation, and mood regulation, though the body of clinical evidence remains limited and primarily exploratory
For example, HO-1 shows dual abilities and can promote or inhibit ferroptosis [109]

[DOI] [PubMed] [Google Scholar] 188.Chanana P., Kumar A

From Lab Curiosity to Skincare Staple This connection was the lightbulb moment that kicked off a wave of new research