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You may still be able to pass stool if it has not fully blocked the rectum

PTI leads to the production of reactive oxygen species (ROS), activation of mitogen-activated protein kinase (MAPK) cascades, G-proteins, ubiquitin, calcium, hormones, transcription factors (TFs), and epigenetic modifications that regulate the expression of pathogenesis-related (PR) genes 7,8,9,10,11

doi: 10.1016/S0140-6736(96)07493-4

Role of Calcium and Magnesium Infusion in Prevention of Oxaliplatin Neurotoxicity
