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Intravesical treatments with heparin, hyaluronic acid, chondroitin sulfate, bacillus Calmette-Guerin, dimethylsulfoxide, and resiniferatoxin have been effective in treating IC/BPS, but the effects were not durable (Hanno et al., 2015)

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Its important to point out that while the term healing crisis is often used in complementary and alternative medicine (CAM), research on the phenomenon is very limited
doi:10.3390/pharmaceutics14030588 153

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