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Liang C, Zhang X, Yang M, Dong X

Here's to a company doing incredible work in personalized medicine, and to a team I'm so lucky to call my own

Histamine Histamine Plays an Important Role in Promoting and Stabilizing Wakefulness 1-3 Histamine promotes wakefulness by activating cortical, subcortical, and wake-promoting neurons and helps stabilize wakefulness by inhibiting sleep-promoting neurons (non-REM and REM) 1-4 Several other neuronal systems are involved in wakefulness and non-REM and REM sleep, including acetylcholine, dopamine, norepinephrine, and serotonin 5

While the clinical translation is still in its early days, the mechanistic rationale is compelling, and the preclinical evidence is impressive

Oxidative lipidomics: analysis of oxidized lipids and lipid peroxidation in biological systems with relevance to health and disease, in Measuring oxidants and oxidative stress in biological systems
