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Surgery 110 , 192198 (1991)

For instance, transplantation of gut microbiota from AUD patients into mice induced a decrease in BHBA metabolism that may be associated with social impairment and depression in AUD (221)

Since homovanillic acid (HVA) is the major metabolite of dopamine and vanillylmandelic acid (VMA) is the major metabolite of both epinephrine and norepinephrine, the measurement of the HVA/VMA ratio is a good indicator of inhibition of DBH in the presence of high Clostridia metabolites

In rat models, BPC-157 significantly improved healing of transected Achilles tendons and medial collateral ligaments, supporting its role in soft tissue regeneration. Chang et al., Journal of Orthopaedic Research 4

Small sample sizes, research design variability (eg, different patient demographics, formulations, and doses), brief follow-up periods, and uneven biomarker validation are some of the main drawbacks