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You should feel warmer, start to sweat a little, and take deeper breaths

Canada contributes a complementary regulatory environment: Health Canada issued enabling virtual trial guidance in 2022 and has since participated in FDA-EMA bilateral discussions on DCT standards harmonization, reducing friction for North American sponsors designing protocols for simultaneous US-Canada submission

Avoid intramuscular injection unless specifically directed by a supervising clinician

Park H-J, Salem M, Semlali A, et al

This lack of delay would represent a major advantage if translatable to humans, given that conventional antidepressants typically require 2-6 weeks before patients experience relief