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Randomization, blinding, and intervention Following a 2-week run-in period, the participants were randomly allocated to the L-carnitine + synbiotic or L-carnitine + placebo groups via block randomization in a 1:1 ratio, in blocks of two, stratified by age, using the Random Allocation Software (RAS)

We did not observe differences in sensitivity to olaparib in HR-deficient models following TMLHE knockdown alone or combined with KG, l-carnitine or acetylcarnitine supplementation (Extended Data Fig

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