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Clinical consequences include spider telangiectasias and palmar erythema, gynecomastia in men, and abnormal vaginal bleeding and irregular menstrual periods in women

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Abbreviations The following abbreviations are used in this manuscript: Supplementary Materials The following supporting information can be downloaded at: Supplementary Table S1

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Moreover, this option is expensive and difficult to develop in some centers ( Cryopreserving sperm is impossible in prepuberal patients

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In addition, salivary HO-1 concentrations in patients with early-stage PD appeared to be considerably greater than in healthy controls (Song et al., 2018)

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