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Notably, ferroptotic cell death in a pancreatic Gpx4 conditional knockout mouse model further promotes tissue injury and inflammation in experimental pancreatitis [513]
doi: 10.1038/sj.emboj.7601369
Circulating IL-6 levels are also increased in insulin resistant states such as obesity, impaired glucose tolerance, and type 1 and 2 diabetes (1, 3, 69)
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