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The present narrative review is part of a larger project, and we present this companion article that provides a detailed examination of the literature beyond bioactives for estrogen-deficient skin covering the polyphenols (i.e., daidzein, genistein, equol, and resveratrol) [9]

I.GoharM.MunsifF.et al

Activation of the NF-B pathway leads to the increased production of ROS, creating a positive feedback loop that amplifies oxidative stress and promotes cell apoptosis, contributing to tissue damage and organ failure [228]

It is, however, noteworthy to mention that for a number of glycolytic enzymes, we did not find the reported most critical cysteine residue (i.e., the active-site cysteine or key cysteine for enzymatic function) to be more oxidized in tumors

Enhanced oxidative resilience safeguards thyroid follicular cells, preserves hormone synthesis capacity, and supports long-term functional recovery in patients with hypothyroidism