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Using multi-omic and bioenergetics analyses, a recent study demonstrated that high-OXPHOS ovarian cancer cells with higher ROS content exhibited greater sensitivity to taxane and platinum treatment compared to low-OXPHOS cells [58]

Genetic Factors Affecting Methionine Metabolism Impairment in any process during the methionine cycle could conceivably affect methionine metabolism

(2022), writing in Frontiers in Pharmacology , conducted the most thorough preclinical study across rats and beagle dogs

By addressing these knowledge gaps, future research can pave the way for the rational development of ferritin-targeted clinical strategies to enhance therapeutic response, overcome resistance, and improve outcomes in brain cancer patients