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Typically it breaks down to one week in Japan for paperwork and customs, two weeks by boat and one week in US customs/clearance

doi: 10.1016/j.celrep.2019.10.070 65 KinowakiYKurataMIshibashiSIkedaMTatsuzawaAYamamotoMet al

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Furthermore, only 9.5% of the treated patients were considered non-responders, compared to nearly 26% of the control group
Concerns exist regarding effects on existing moles and potential melanoma risk, though causality has not been established
