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We hypothesized that the observed lower GSH:GSSG ratio in asthmatic lung fluids and cells is at least partially driven by high oxidation of GSH and its export in response to greater intracellular 15LO1/PEBP1 pathway activity

Moreover, there is an increasing consensus that FSP1 significantly reduces ROS and promotes the differentiation of oocyte cells and brown adipocytes, although the specific molecular mechanism remains unclear (Nguyen et al

10.1136/gut.48.3.347 70

16 All these previous studies regarding skin temperature and most of the studies concerning core body temperature were performed in a laboratory setting, but whether laboratory findings are representative for actual daily life has not been assessed
