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Moreover, astrocytes facilitate lymphocyte movement across the blood-brain barrier, engage in antigen presentation between lymphocytes and microglia, and activate peripheral B cells and T cells via the lymphatic system, thereby amplifying the cerebral inflammatory cascade (1,8,9)

Apart from direct antagonism, the endophyte also triggers ROS production, resulting in inhibition of the mycelial growth and spore germination, activation of the defense enzymes peroxidase, chitinase, and beta-1,3-glucanase, and inhibition of mycelial growth, spore germination, and phenyl alanine ammonia lyase that regulate plant growth and stress tolerance

Combination of Gold Nanoparticles With Carnitine Attenuates Brain Damage in an Obesity Animal Model. Molecular Neurobiology 61: 63666382

The role of gut-derived lipopolysaccharides and the intestinal barrier in fatty liver diseases

Its status in research is that of a synthetic cytoprotective agent a compound studied for its ability to protect and restore tissue integrity across multiple organ systems in animal models [8]