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) and extremely reactive hydroxyl radical (

This suggested that SF was exerting a pharmacodynamic action that reflected induction of GSTs by SF, thereby shunting the reactive epoxide intermediate away from nucleophiles in DNA, where it would have mutagenic and carcinogenic effects, and toward GSH, which allowed it to be further metabolized and excreted in the urine

Trimmer PA, Keeney PM, Borland MK, Simon FA, Almeida J, et al

Higher doses or more frequent use increase monthly expenses
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