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Consult a healthcare practitioner prior to use if you are pregnant or breastfeeding, have kidney disease, or have a seizure disorder

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Interventions The IM arm received 1 mg VB12 on alternate days in weeks 12, 1 mg/week in weeks 38 and 1 mg/month in weeks 952

Here, Cui and colleagues discuss the mechanisms that lead to leptin and ghrelin resistance, and how they might be exploited as targets for the management and treatment of obesity.