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While pyridoxine (vitamin B6) is typically considered helpful in reducing vomiting and nausea, the American Academy of Family Physicians (AAFP) mentions that cyanocobalamin (vitamin B12) also significantly reduced vomiting episodes in pregnant women compared with placebo, indicating its role in nausea and vomiting management

A little bit is broken down there, but the rest reaches the small intestine and is absorbed into the bloodstream

One systematic review and network meta-analysis of thirteen studies, published in Springer, evaluated three administration routes of vitamin B12: oral, intramuscular, and sublingual routes

Comment: A commenter suggested that CMS consider including language that promotes avoidance of the IDR process when findings surpass a certain level of seriousness

Vitamin B12, also known as cobalamin, is an essential vitamin that your body needs but cannot produce