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The primary structure of the human cysteinylglycine dipeptidase has been deduced from the cDNA by Adachi et al

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Thus, in human endothelial cells, we found that adhesion molecules, such as vascular adhesion molecule 1 (VCAM1) and intercellular adhesion molecule 1 (ICAM1), are upregulated by the absence of GPx1 and the expression of adhesion molecules is further augmented with exposure to TNF or lipopolysaccharide