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Anaphylaxis has not been widely reported with nasal formulations, but any breathing difficulty or rapid heartbeat after dosing warrants immediate emergency care

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Blood-brain barrier disruption is increasingly recognized as a key mechanism underlying CSVD progression

Mesenchymal stem cells from adipose and bone marrow promote angiogenesis via distinct cytokine and protease expression mechanisms

doi: 10.1111/j.1749-6632.2012.06538.x PMCID: PMC3384703 NIHMSID: NIHMS366557 Zonulin, regulation of tight junctions, and autoimmune diseases Alessio Fasano ~ Physiol Rev
