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The G-site is located at the N-terminus and is the specific binding site for glutathione (GSH)

The protein used for activity measurement was eluted without GSH (Sigma) in elution buffer and further buffer exchanged to 25 mM Tris-HCl pH 7.8, 100 mM NaCl, 10% (v/v) glycerol, 5 mM 2-mercaptoethanol, and 0.05% (w/v) DDM using PD-10 columns (GE Healthcare)

Many products marketed as liposomal supplements dont contain any liposomes at all and use inferior ingredients, 1 so it's important to be well-informed when choosing a glutathione product that you can trust

The glutathione may help in regulating melanin formulation

Brager MA, Patterson MJ, Connolly JF, Nevo Z