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Malaria remains a major global health problem, particularly in tropical and subtropical regions, where resistance to existing antimalarial drugs, such as chloroquine and artemisinin-based therapies, is an escalating issue

Isobolographic analysis was implemented to determine if the interaction between two drugs given in combination is synergistic (supra-additive), additive, or antagonistic (infra-additive) [26, 27]

However, miR-144-3p, derived from osteosarcoma cell exosomes, negatively regulates ZEB1 expression, influencing iron metabolism and ROS levels to induce ferroptosis in cancer cells [45]

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