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Figure 2 shows the proposed molecular mechanism of action

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Many natural antioxidants taken from diet or from supplements have very limited bioavailability and their in vitro antioxidant activity and ability to regenerate themselves have not been confirmed in cells or tissues (Jomova et al

Even worse, vitamin C increased cell viability in CRC cells with low SVCT-2 expression, suggesting that vitamin C has a biphasic effect depending on its cellular uptake