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e.g., cholesterol depletion reduces Ca 2+ -dependent exocytosis of large dense-core vesicles (LDCVs) 17 , cortical secretory vesicles 18 , and synaptic vesicles in hippocampal neurons 9,19 , cortical synaptosomes 20 , ribbon synapses 21 , and motor nerve terminals 22

Expression of sod-3 in intestinal cells is a reliable marker of DAF-16 antiaging activity 42

On average, people on Tirzepatide lose 26% of their weight in a year*

Most of what is marketed for the brain belongs to the first camp, a smaller and more demanding set belongs to the second, and a few interventions fall between them

doi: 10.1523/JNEUROSCI.1253-12.2012
