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As a supplement to dietary restrictions, it has proven highly beneficial in patients with familial chylomicronemia syndrome (FCS) lowering TGs levels by 7080% [140,141] and this represents a promising start for future drugs targeting ApoC-III

In other types of cancer, such as breast cancer, there is evidence that exosomes derived from human mesenchymal stem/stromal cells (hMSCs) can enhance proliferation and metastasis in this type of cancer

preventing sphingomyelin breakdown, inhibiting caspase-3 activation, reducing cell death, and increasing erythrocyte survival [263, 264]

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