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Glutathione amplifies the bodys antioxidant defenses, acting as a cofactor for antioxidant enzymes and regenerating oxidized vitamins C and E

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These results could not be attributed to differences in mitochondrial oxidative activity or to increased apoptotic cell death

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Quantification of cytosolic glutathione redox potential leads to the discovery that the ABC-C transporter Ycf1 rapidly transports oxidized glutathione (GSSG) into vacuoles and whole-cell GSSG should not be used as a proxy for cytosolic GSSG.