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Ferroptosis in musculoskeletal diseases Musculoskeletal diseases, such as osteoarthritis, osteoporosis, sarcopenia, and amyotrophic lateral sclerosis, seriously impair patients quality of life and place a substantial strain on global public health resources
In Orai1 knockout mice, the LPS-induced depression-like behavior, including the helplessness and pleasure deficit, is improved in astrocytes (Novakovic et al., 2023)

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