glutathione catabolism where metabolic pathways. GCL, glutamate cysteine ligase; GST, Cysteine metabolic circuitries: druggable targets
Description
Hagen,Identification of age-specific Nrf2 binding to a novel antioxidant response element locus in the Gclc promoter: a compensatory means for the loss of glutathione synthetic capacity in the aging rat liver?Aging Cell, 2012
Our cells have adapted to this potential toxicity by storing cysteine in the form of glutathione (GSH) [8] , which is far more stable to oxidation
Cell Signal 132, 111813
10.1016/j.jaad.2019.05.094 J Am Acad Dermatol
doi: 10.3109/10428199409049647 84 RuvoloPPHuCWQiuYRuvoloVRGoRLHubnerSEet al
