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Obtain new stocks of cells, and use them with fresh media and reagents

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Human GH circulates partially bound to two GH binding proteins: a high-affinity GH-BP binds 85-90% of circulating GH, and a low-affinity GH-BP binds the rest

This strategy enabled the synthesis of the natural product abieta6,8,11,13-tetraen-18-oic acid ( 30 ) 53 after the amide hydrolysis of 29 with NOBF 4
