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What was striking about the T-cell response in the HCWs with abortive infection was the enrichment for T cells targeting the conserved nonstructural proteins of open reading frame 1ab (ORF1ab), which make up the core of the RTC [67]

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Published data from growth hormone axis studies demonstrates that this pulsatile delivery pattern more accurately mimics endogenous GHRH secretion rhythms compared to continuous infusion models

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