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doi: 10.1080/15592294.2022.2163363 44 CapucoA

Differences lie in how raw materials are sourced and processed

The glucose-6-phosphotase (G6Pase) complex, which localizes to the endoplasmic reticulum membrane, converts G6P to glucose, to maintain glucose and glycogen balance, rendering neutrophils the only leucocytes equipped with both gluconeogenesis and glycogenesis abilities (54)

These intracellular events are dynamically coupled with intercellular communication and microenvironment remodeling to jointly promote DTP survival and further tumor progression