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A ROC curve was built using only the metabolites with a significant statistical variation, and the area under the curve of the ROC analysis was found to be 0.842 (95% CI: 0.7350.949), indicating high predictive accuracy of the model and thus a good discriminative ability of the metabolites to accurately differentiate between subjects with PsA and HC (Fig

Altered human oligodendrocyte heterogeneity in multiple sclerosis

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Similarly, macrophages use glutamine for arginine and thus nitric oxide (NO) synthesis through the action of the inducible NO synthase (iNOS) enzyme, by using NADPH as an energy source