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(2008) The x c cystine/glutamate antiporter: a potential target for therapy of cancer and other diseases, J
They can circulate in the bloodstream for several days, which is beneficial for drug delivery, especially for some drugs that tend to cause immune reactions

Others may need a few days more

A spreadsheet with pathogenicity log likelihood ratios and delta (remediability) scores can be found in Additional file 6: Table S4
Thermolabile 5,10-methylenetetrahydrofolate reductase as a cause of mild hyperhomocysteinemia