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Based on structural and functional similarities, the superfamily is divided into 5 main subfamilies: Ras, Ran, Rho, Arf and Rab family

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Lactate dehydrogenase (LDH) release and ATP levels confirmed these protective effects, showing a reduction in LDH release from 212.29% to 122.98% and restoring mitochondrial membrane potential to 94.62% at 50 M of the puerarin-loaded PLGA nanoparticles