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The underlying mechanisms of the actions of sulforaphane on cytochrome P450 expression is unclear, but may relate in part to cross-talk between the Nrf2 and Aryl hydrocarbon receptor (Ahr) pathways 26
Teardo E, Carraretto L, De Bortoli S, Costa A, Behera S, Wagner R, Lo Schiavo F, Formentin E, Szab I (2014) Alternative splicing-mediated targeting of the Arabidopsis glutamate receptor 3.5 to mitochondria affects organelle morphology
Other TP53 target genes, including CDKN1A/p21 (cyclin dependent kinase inhibitor 1A), PMAIP1/NOXA (phorbol-12-myristate-13-acetate-induced protein 1), and BBC3/PUMA (BCL2 binding component 3), coordinately regulate copper-induced apoptosis
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