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484 NDDs include diseases such as AD, PD, Huntingtons disease (HD), and ALS, which are characterized by a progressive dysfunction and loss of neurons in specific brain regions, leading to symptoms such as cognitive and motor deficits (e.g., dementia and tremors)

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Although multiple metabolic routes have been shown to be affected in NF1 tumorigenesis, metabolic based anti-neoplastic approaches are limited in the field (BeGIN clinical trial) and others are at the preclinical stage (Figure 3)

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Depletion of glutathione affects root development also by interfering with auxin transport 84,89,90

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Figure 4 and Supplementary Figs S2 and S3 illustrate the endpoint morphology of the cells under each of the 4 conditions described above

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Take a moment to reset, recharge, and prioritise your wellbeing

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