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A peripheral signature of Alzheimers disease featuring microbiota-gut-brain axis markers

L-carnitine plays a vital role in the -oxidation of long chain fatty acids (LCFAs) to produce energy by transporting LCFAs from the cytosol into the mitochondrial matrix, and can modulate the ratio of acetyl-CoA/CoA 3,4

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In the overnight fasted state and during exercise of low to moderate intensity, long chain fatty acids are the main energy source of energy used by most tissues, including skeletal muscle