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GSH supplementation restored erlotinib sensitivity in resistant cells, while GSH reduction in sensitive cells induced resistance

10.1074/jbc.275.14.10405 J

Histological analysis of myocardium Micrographs of Masson's trichrome-stained myocardial section are shown in Figure 3a

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Nicotinamide and EGCG reduce A accumulation and protein oxidation in aged 3xTg-AD hippocampal neurons Since intracellular A aggregates increase across the lifespan of the 3xTg-AD model in vivo [38], and in vitro [1] and a hallmark for brain aging and the progression of AD is protein oxidation, including tyrosine nitration [1, 39], we immunostained neurons for A accumulation and protein nitration and evaluated the effects of treatment with nicotinamide and EGCG