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10.1038/sj.onc.1202237 261

One study reported that KD significantly reduced the diversity of the intestinal flora, but at the same time, Parabacteroides and Akkermansia muciniphila increased during KD intake ( 4.3 Oxidative stress and inflammatory pathways Disturbances in mitochondrial energy metabolism and reactive oxygen species (ROS) production are key players in many diseases

Lactobacillus and Pediococcus ameliorate progression of non-alcoholic fatty liver disease through modulation of the gut microbiome

Alternative therapies in health and medicine, 30 (10), 1217

An ideal strategy should integrate imaging such as quantitative MRI parameters, fluid aspiration measuring MDA, 4-HNE, iron metabolism indicators, and GPX4-related protein/nucleic acid levels, and advanced omics analyses to build a comprehensive risk assessment system for predicting ferroptosis activity and treatment response (Lotz et al., 2013)